Metoprolol Succinate (50 mg) Extended-Release + Chlorthalidone (12.5 mg) Tablet is a combination antihypertensive medicine used for the treatment of hypertension (high blood pressure) and to reduce the risk of cardiovascular complications. Metoprolol, a selective beta-1 adrenergic blocker, slows the heart rate and decreases the heart's workload, while Chlorthalidone, a thiazide-like diuretic, removes excess sodium and water from the body, helping to lower blood pressure. This combination provides sustained 24-hour blood pressure control, improves cardiovascular function, and helps reduce the risk of heart attack, stroke, heart failure, and kidney damage associated with uncontrolled hypertension.